Source: RGD

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7038
Gene Symbol: TG
TG
thyroglobulin 0.480 0.808 2.9E-59
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.400 None 1.000 1 0 1986 2020
Entrez Id: 7200
Gene Symbol: TRH
TRH
thyrotropin releasing hormone 0.519 0.846 8.9E-04
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.290 None 1.000 1 0 1978 2019
Entrez Id: 9572
Gene Symbol: NR1D1
NR1D1
nuclear receptor subfamily 1 group D member 1 0.608 0.692 0.82
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.230 None 1.000 1 0 1992 2019
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
insulin like growth factor 1 0.318 0.885 0.27
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.270 None 1.000 1 0 1992 2019
Entrez Id: 3586
Gene Symbol: IL10
IL10
interleukin 10 0.281 0.923 5.9E-03
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.210 None 0.500 1 0 2014 2019
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
nitric oxide synthase 3 0.378 0.885 6.7E-07
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.210 None 1.000 1 0 1997 2018
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
cytochrome P450 family 19 subfamily A member 1 0.410 0.885 1.7E-05
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.210 None 1.000 1 0 2010 2018
Entrez Id: 1641
Gene Symbol: DCX
DCX
doublecortin 0.511 0.769 0.30
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.210 None 1.000 1 0 2012 2018
Entrez Id: 627
Gene Symbol: BDNF
BDNF
brain derived neurotrophic factor 0.345 0.923 0.66
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.220 None 1.000 1 0 2010 2018
Entrez Id: 9611
Gene Symbol: NCOR1
NCOR1
nuclear receptor corepressor 1 0.597 0.731 1.00
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.220 None 1.000 1 0 2000 2017
Entrez Id: 5111
Gene Symbol: PCNA
PCNA
proliferating cell nuclear antigen 0.382 0.846 0.98
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.210 None 1.000 1 0 2011 2017
Entrez Id: 488
Gene Symbol: ATP2A2
ATP2A2
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 0.529 0.808 1.00
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.220 None 1.000 1 0 1999 2015
Entrez Id: 8851
Gene Symbol: CDK5R1
CDK5R1
cyclin dependent kinase 5 regulatory subunit 1 0.529 0.808 0.91
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.200 None 1.000 1 0 2014 2014
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
superoxide dismutase 1 0.379 0.962 0.18
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.210 None 1.000 2 0 2003 2012
Entrez Id: 2876
Gene Symbol: GPX1
GPX1
glutathione peroxidase 1 0.458 0.923 3.9E-05
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.200 None 1.000 1 0 2012 2012
Entrez Id: 572
Gene Symbol: BAD
BAD
BCL2 associated agonist of cell death 0.553 0.769 4.6E-03
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.200 None 1.000 1 0 2011 2011
Entrez Id: 857
Gene Symbol: CAV1
CAV1
caveolin 1 0.388 0.885 8.3E-03
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.200 None 1.000 1 0 2011 2011
Entrez Id: 4900
Gene Symbol: NRGN
NRGN
neurogranin 0.608 0.615 0.48
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.200 None 1.000 2 0 2005 2010
Entrez Id: 539
Gene Symbol: ATP5PO
ATP5PO
ATP synthase peripheral stalk subunit OSCP 0.861 0.192 5.8E-02
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.200 None 1.000 2 0 1998 2010
Entrez Id: 4684
Gene Symbol: NCAM1
NCAM1
neural cell adhesion molecule 1 0.415 0.885 1.00
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.210 None 1.000 1 0 2010 2010
Entrez Id: 7351
Gene Symbol: UCP2
UCP2
uncoupling protein 2 0.493 0.808 1.5E-10
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.210 None 1.000 1 0 2010 2010
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
nitric oxide synthase 2 0.364 0.923 4.0E-15
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.200 None 1.000 1 0 2010 2010
Entrez Id: 6715
Gene Symbol: SRD5A1
SRD5A1
steroid 5 alpha-reductase 1 0.631 0.538 1.2E-05
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.200 None 1.000 1 0 2010 2010
Entrez Id: 157
Gene Symbol: GRK3
GRK3
G protein-coupled receptor kinase 3 0.621 0.731 0.71
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.200 None 1.000 1 0 2010 2010
Entrez Id: 80339
Gene Symbol: PNPLA3
PNPLA3
patatin like phospholipase domain containing 3 0.556 0.692 5.7E-08
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.210 None 1.000 1 0 2009 2009